What are the stages of encephalopathy?
Amelia Brooks
Updated on March 08, 2026
What are the stages of encephalopathy?
Table 1: West-Haven Criteria for Hepatic Encephalopathy (HE)
| Stage | Consciousness | Neurologic Findings |
|---|---|---|
| 1 | Mild lack of awareness | Impaired addition or subtraction; mild asterixis or tremor |
| 2 | Lethargic | Obvious asterixis; Slurred speech |
| 3 | Somnolent but arousable | Muscular rigidity and clonus; Hyperreflexia |
| 4 | Coma | Decerebrate posturing |
What is hepatic encephalopathy grade2?
Grade 2: lethargy or apathy, minimal disorientation for time or place, subtle personality change, inappropriate behaviour, impaired performance of subtraction. Grade 3: somnolence to semi stupor but responsive to verbal stimuli, confusion, gross disorientation. Grade 4: coma (unresponsive to verbal or noxious stimuli).
What are the grades of hepatic encephalopathy?
Until recent years, the term “overt” hepatic encephalopathy was applied to patients with grades 1 through 4 encephalopathy. Now, patients with grades 0 and 1 hepatic encephalopathy are said to be “covert”; patients with grades 2 through 4 hepatic encephalopathy are said to be “overt.”
How serious is encephalopathy?
Encephalopathy is not a single disease but a group of disorders with several causes. It’s a serious health problem that, without treatment, can cause temporary or permanent brain damage. It’s easy to confuse encephalopathy with encephalitis.
Can encephalopathy be cured?
Many forms of encephalopathy are reversible if the cause can be identified and treated. All types can be fatal if severe enough. Some types are always fatal.
How do you get encephalopathy?
The causes of encephalopathy are numerous and varied; they include infections, anoxia, metabolic problems, toxins, drugs, physiologic changes, trauma, and other causes. Encephalopathy is a general term that means brain disease, damage, or malfunction. The major symptom of encephalopathy is an altered mental state.
How long does encephalopathy last?
According to the National Institute of Neurological Disorders and Stroke , transmissible spongiform encephalopathy usually results in death within three months to a few years from the onset of the disease. Treatment for the cause of your brain disease may improve your symptoms or may get rid of the encephalopathy.
How long does someone live with hepatic encephalopathy?
In patients with compensated cirrhosis, median survival is greater than 12 years. By contrast, in patients experiencing a decompensation, commonly defined by ascites, hepatic encephalopathy (HE), variceal haemorrhage and jaundice, survival is far shorter at two years or less[3-5].
How can encephalopathy be prevented?
How can I prevent hepatic encephalopathy?
- Avoid alcohol, which damages liver cells.
- Avoid medications that affect the nervous system, such as sleeping pills and antidepressants.
- Eat a nutritious diet, exercise and maintain a healthy weight (especially important if you have fatty liver disease).
Is encephalopathy a disability?
The symptoms of toxic encephalopathy can be debilitating and often totally disabling, making it difficult, if not impossible, for patients to hold a job and maintain their normal way of life.
Can encephalopathy cause death?
Some encephalopathies can be fatal. Treating the underlying cause of the disorder may improve symptoms. However, the encephalopathy may cause permanent structural changes and irreversible damage to the brain. Some encephalopathies can be fatal.