What are the side effects of taking saxagliptin?
Michael King
Updated on March 10, 2026
What are the side effects of taking saxagliptin?
5. Side effects
- feeling dizzy or weak.
- headaches.
- diarrhoea.
- stomach pains.
- feeling or being sick (nausea or vomiting)
- urinary tract infections (UTIs)
- cold-like symptoms.
- mild rash.
What time of day should I take saxagliptin?
You can generally take the tablet at a time of day to suit you, but it is best to take your doses at the same time of day each day. You can take saxagliptin before or after a meal.
What are the side effects of using tablets?
Common minor side effects of prescription drugs:
- Diarrhea.
- Dizziness.
- Drowsiness.
- Fatigue.
- Heart issues (palpitations, irregular heartbeats)
- Hives.
- Nausea and vomiting.
- Rash.
How often can you take saxagliptin?
Adults—At first, one tablet containing 5 milligrams (mg) of saxagliptin and 500 mg of metformin once a day. Your doctor may adjust your dose until your blood sugar is controlled. However, the dose is usually not more than 5 mg of saxagliptin and 2000 mg of metformin once a day.
Can saxagliptin cause heart failure?
[ 4-5-2016 ] A U.S. Food and Drug Administration (FDA) safety review has found that type 2 diabetes medicines containing saxagliptin and alogliptin may increase the risk of heart failure, particularly in patients who already have heart or kidney disease.
Can saxagliptin cause hypoglycemia?
Although saxagliptin by itself usually does not cause low blood sugar (hypoglycemia), low blood sugar may occur if this drug is prescribed with other diabetes medications. Talk with your doctor or pharmacist about all your diabetes medication(s).
What are severe side effects?
A side effect is considered serious if the result is: death; life-threatening; hospitalization; disability or permanent damage; or exposure prior to conception or during pregnancy caused birth defect. increase or decrease the dose (amount) of a drug that you take.
What are 5 side effects of drugs?
Side effects of drug addiction may include: Nausea and abdominal pain, which can also lead to changes in appetite and weight loss. Increased strain on the liver, which puts the person at risk of significant liver damage or liver failure. Seizures, stroke, mental confusion and brain damage. Lung disease.
How do you take saxagliptin tablets?
Saxagliptin comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take saxagliptin at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Is saxagliptin safe in heart failure?
Safety Announcement [ 4-5-2016 ] A U.S. Food and Drug Administration (FDA) safety review has found that type 2 diabetes medicines containing saxagliptin and alogliptin may increase the risk of heart failure, particularly in patients who already have heart or kidney disease.
Can saxagliptin cause pancreatitis?
Sitagliptin-induced pancreatitis can occur at any time after the initiation of therapy, even after several years.
What drugs have the worst side effects?
New Research Exposes The 15 Most Dangerous Drugs
- Acetaminophen (Tylenol) Common names for Acetaminophen include Tylenol, Mapap, and Feverall.
- Alcohol. Alcohol includes all types of beer, wine, and malt liquor.
- Benzodiazepines.
- Anticoagulants.
- Antidepressants.
- Anti-Hypertensives.
- Bromocriptine.
- Clarithromycin.
Does saxagliptin make you put on weight?
You take saxagliptin once a day. The most common side effects of saxagliptin are diarrhoea or stomach ache. This medicine does not usually make you put on weight. Saxagliptin is also called by the brand name Onglyza. When combined with metformin it’s called Komboglyze, and Qtern when mixed with dapagliflozin.
What do ONGLYZA (saxagliptin) tablets look like?
ONGLYZA (saxagliptin) 2.5 mg tablets are pale yellow to light yellow, biconvex, round, film-coated tablets with “2.5” printed on one side and “4214” printed on the reverse side, in blue ink. ONGLYZA (saxagliptin) tablets have markings on both sides and are available in the strengths and packages listed in Table 15.
Can I take saxagliptin If I am pregnant or breastfeeding?
Saxagliptin is generally not recommended in pregnancy or while breastfeeding. Your doctor will only prescribe saxagliptin while you’re pregnant or breastfeeding if the benefits of taking the medicine outweigh the risks. Small amounts of saxagliptin get into breast milk. But it has not been linked with any side effects in breastfed babies.
What are the possible adverse effects of saxagliptin and thiazolidinedione?
Commonly reported adverse reactions include respiratory tract infection, urinary tract infection, and headache. Peripheral edema was more commonly reported in patients treated with the combination saxagliptin and thiazolidinedione.